alternated c absence of positive therapeutic action.
There are data on positive therapeutic effect of intake And at sharp displays the HELL. This information is confirmed during the open tests, and also eight-week, double 'blind', -controllable, cross research. As system application And is accompanied by well-known undesirable collateral actions, attempts of its his local application have been undertaken. However local application And, apparently, does not render essential medical influence at the HELL: as a result of three-week 'blind' research of efficiency 10 %-s' gels and 10 %-s' ointments Instead of are revealed substantial improvement of a condition of patients the HELL.
There are single data on test - preparations of a new class with the structure, possessing significant activity. The transplant concerns to this group of preparations against the owner ' , or FR506, initially registered with the purpose of suppression of reaction '. However during researches it has been shown its his significant activity and at other diseases. To the same group of preparations concerns Ascomycin derivative SDZ ASM 981. Owing to chemical structure of these preparations they can be applied at the HELL. These preparations are 4-; on force of action they with , but do not possess by-effects, characteristic for . It is shown, that application in the form of ointment in
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